Endocrine Abstracts

Persistent Mullerian duct syndrome (PMDS) is a rare disorder of sex development characterized by the persistence of Mullerian duct derivatives in a genotypic (46,XY) and phenotypic normally virilised male. PMDS is transmitted in an autosomal recessive manner, caused by mutations in the anti-Mullerian hormone gene or in the gene encoding the AMH receptor. The authors report a case of a male patient aged 62 years, with bipolar disorder, referred to the endocrinologist by inciden...

Introduction: Amiodarone is an antiarrhythmic iodine-rich drug, known to induce thyroid dysfunction both due to its high iodine content and through amiodarone-induced thyrotoxicosis (AIT), being this latter process classified into three different types. Type 1 is associated with increased thyroid hormone synthesis; type 2 is a destructive process with thyroid hormone release and type 3 is thought to be a mixture of the former two. Since treatment options are different, there h...

Background and objective: According to recent studies, endocrine societies have modified the treatment criteria of subclinical gestational hypothyroidism, increasing TSH upper-limit value commonly set at 2.5 μU/ml to a new threshold set at 4 μU/ml. This change in criteria has responded to numerous studies which seem to indicate that the obstetrical complications do not generally increase despite this variation of the threshold TSH value. A further discussion lays now...

Introduction: Bariatric surgery has proved to be effective in the management of morbid obesity. Our purpose was to compare the results obtained with adjustable gastric banding (GB) and Roux-en-Y Gastric Bypass (RYGB) during 2 years of follow-up after surgery, with regard to anthropometric parameters and related comorbidities.Methods: We evaluated prospectively patients who underwent GB and RYGB between 2004 and 2010 and compared the evolution of anthropo...

Introduction: Bariatric surgery is associated with improvement and often resolution of type 2 diabetes mellitus (T2DM). Our aim was to compare the effects of gastric banding (GB) and gastric bypass (GBP) in glucose homeostasis in obese patients with T2DM.Methods: From 1995 to 2011, 83 diabetic patients underwent bariatric surgery at our hospital: 37 underwent GB (73% females, mean age 48.3±9.2) and 46 underwent GBP (82.6% females, mean age ...